Simon Willison announced the first release of Datasette Agent, merging his 'llm' Python library with Datasette. The tool provides a conversational interface to query SQLite databases, with plugin support for generating charts and running code in sandboxes. It runs efficiently on lightweight models like Gemini 3.1 Flash-Lite and supports local open-weight models via LM Studio.
This report explores the latest breakthroughs made by AI science assistants in the field of "drug repurposing" (also known as drug retargeting — finding new…